One of the most comprehensive Biologics portfolios within the market today.
The Zimmer Biomet Biologics product portfolio represents the passionate pursuit of the most innovative and clinically relevant solutions addressing the needs of surgeons and their patients. As a leader in autologous therapies, Zimmer Biomet Biologics offers a myriad of solutions for hard tissue applications, but also for soft tissue management.
Autologous cellular therapies are at the forefront of regenerative medicine. Such treatment options include blood and bone marrow aspirate and concentration.
Zimmer Biomet offers Platelet-Rich Plasma (PRP) products to produce PRP which can be mixed with autograft or allograft materials.
Zimmer Biomet offers a host of ancillary products which help support and manage the delivery of our extensive product portfolio.
The philosophy defining our hard tissue products is based on the
complex process involved in tissue repair, wherein the matrix/scaffold
(osteoconductive), signaling proteins (osteopromotive* and/or
osteoinductive), and tissue forming cells (osteogenic) work in concert
to form new tissue (bone).3
Although autograft is considered the gold standard for orthopedic procedures requiring graft material, it has known limitations with associated donor site morbidity and limited availability.4 Synthetic bone graft substitutes have been developed to overcome these limitations of donor site morbidity and limited availability.
* Products that produce a PRP output do not currently have FDA clearance to be characterized with a specific mechanism of action. PRP, in and of itself (i.e., without the autograft or allograft), is not FDA cleared as “osteopromotive.”
Viable Cellular Matrix
Zimmer Biomet offers human tissue allograft possessing all three of the components of the bone remodeling triad: osteoconductivity, osteoinductivity and osteogenicity.
The cartilage repair solutions from Zimmer Biomet can be used to address osteochondral deficiencies in multiple anatomic locations. They offer a convenient early interventions option that can limit the need for further surgical intervention and potentially divert the progression of these lesions.
Soft Tissue Management
Zimmer Biomet offers soft tissue management products which may be used in various practices including orthopedics, plastic surgery and general surgery.
- Tofighi A., et al. New Generation of Synthetic, Bioresorbable
and Injectable Calcium Phosphate Bone Substitute Materials:
Alpha-bsm, Beta-bsm and Gamma- bsm. Journal of Biomimetics,
Biomaterials and Biomedical Engineering (JBBBE). 2:39, 2009.
- Angle SR, et al. Novel Macroporous Calcium Phosphate Scaffold To Improve Cell Infiltration and Osseous Integration. Transactions of the 61st Annual Meeting of the Orthopaedic Research Society: 1157, 2015.*
- Khan, S. N., et al. The Biology of Bone Grafting. The Journal of the American Academy of Orthopaedic Surgeons. 13(1):77-86, 2005.
*Animal studies are not necessarily indicative of clinical outcomes.
Tailored resources for your patients
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For product information, including indications, contraindications, warnings, precautions, potential adverse effects and patient counseling information, see the package insert or contact your local representative; search this website for additional product information. To obtain a copy of the current Instructions for Use (IFU) for full prescribing and risk information, please call 1-800-348-2759, press 4 for 411 Technical Support.