The complete bone remodeling triad
Osteoconductive. Osteoinductive. Osteogenic.
Bonus Triad Allograft is a cryopreserved human tissue allograft consisting of cancellous bone combined with demineralized cortical bone matrix. This particular combination provides all three components of the bone remodeling triad: osteoconductive, osteoinductive, and osteogenic.1*
- Mesenchymal Stem Cells
Bonus Triad Allograft contains at least750,000 cells/cc
of cancellous tissue with at least 70% cell viability.1
Bonus Triad Allograft has been developed to overcome the limitations of some bone graft substitutes and designed to offer a real alternative to autograft.
Many currently available bone grafting materials have some of the features necessary for successful bone healing, but few possess all three of the components of the bone remodeling triad: osteoconductivity, osteoinductivity and osteogenicity. In an effort to provide a graft material that contains all three components without the need to harvest autograft, advanced fresh-frozen allografts were developed from cadaveric tissue to meet this medical need. These allografts retain osteoconductive and osteoinductive properties as well as naturally inherent osteogenic cells.1
Available in 1, 5, 10, and 15cc sizes
Ease of Use
- Bonus Triad Allograft is packaged in an intuitive, proprietary pre-filled delivery syringe and features a built-in filter that allows for the full preparation of the material directly inside the syringe.
- Cryoprotectice solution frozen at -70°C to preserve cell viability
- The cortical fibers are demineralized and create a cohesive graft that stays together.4
Bonus Triad Intraoperative Use
1. Zimmer Biomet Specification RCS-125. Section 3.5 and 3.6.
2. Pietrzak WS, Woodell-May J, McDonald N. Assay of bone morphogenetic protein -2, -4 and -7 in human demineralized bone matrix. J Craniofac Surg. 2006;17(1):84–90.
3. Wildemann B, Kadow-Romacker A, Haas NP, Schmidmaier G. Quantification of various growth factors in different demineralized bone matrix preparations. J Biomed Mater Res A. 2007;81(2):437–42.
4. ZB Internal Test Report, TR-1019.
*Animal and in vitro studies are not necessarily indicative of clinical performance.
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