Features and Benefits


  • Multiple proven implants including:              Persona® The Personalized Knee®, Vanguard® and NexGen® 1-7
  • Tools for soft tissue balancing and femoral rotation
  • Real-time range of motion assessment
  • Perform multiple techniques including Personalized Alignment™, Gap Balancing, Measured Resection and Hybrid
  • Adapts to surgeon workflow with intuitive user interface


  • Offers surgeons precision and accuracy through cut flow and validation feature, designed to ensure proper alignment in real time. Enables more accurate and more reproducible resections than conventional instrumentation 8
  • Provides high levels of precision in regard to targeted angles and resection thickness 9
  • Less outliers and 100% of cases within 3° of the targeted neutral alignment 8
  • Validates all resection mean differences between target resection and measured resection were below 0.7 and had standard deviations below 1.1 mm 9
  • Fewer outliers for all bone resection angles 8
  • With real-time soft tissue balancing, surgeons can determine resections based on each patient’s soft-tissue and bony anatomy


  • 2D X-ray to 3D bone modeling imaging based on X-Atlas® technology
  • Imageless case option
  • Reduced instrumentation through pre-operative planning


Making the best decision when it matters requires data-driven intelligence.
  • A cornerstone of ZBEdge™, our suite of integrated digital and robotic technologies built to unlock data-powered insights across the continuum of care
  • ZBEdge harnesses data from ROSA Robotics to create new value and capabilities, through an unrivaled user experience, with the goal of improving patient outcomes through informed decision-making by quantifying subjective elements of orthopedic care
  • Capture more objective patient-specific data to aggregate, analyze and quantify results 

Brochures and Resources


ROSA MedEd Events

ZBEdge Supporting Evidence

Zimmer Biomet is committed to supporting the value of our technology with evidence. 


ROSAdvantage Warranty Program

Making the decision to get a knee replacement isn’t easy, but we believe by showing patients that Zimmer Biomet stands behind the products in the ROSA®dvantage program and the surgeons who use the products, they will be a little more at ease.



All content herein is protected by copyright, trademarks and other intellectual property rights, as applicable, owned by or licensed to Zimmer Biomet or its affiliates unless otherwise indicated, and must not be redistributed, duplicated or disclosed, in whole or in part, without the express written consent of Zimmer Biomet.

This material is intended for health care professionals. Distribution to any other recipient is prohibited. 

For product information, including indications, contraindications, warnings, precautions, potential adverse effects and patient counseling information, see the package insert and information on this website. To obtain a copy of the current Instructions for Use (IFU) for full prescribing and risk information, please call 1-800-348-2759, press 4 for 411 Technical Support.

For additional robotic inquiries and concerns, contact 1-855 ROSA BOT.


  1. Zhang, Y., et al. Interfacial Frictional Behavior: Cancellous Bone, Cortical Bone, and a Novel Porous Tantalum Biomaterial. Journal of Musculoskeletal Research. 3(4):, 245-251, 1999.
  2. Bobyn, J.D., et al. Characteristics of Bone In-growth and Interface Mechanics of a New Porous Tantalum Biomaterial. Journal of Bone and Joint Surgery (British). 81-B(5): 907, 1999.
  3. Shirazi-Adl, A., et al. Experimental Determination of Friction Characteristics at the Trabecular Bone / Porous-coated Metal Interface in Cementless Implants. The Journal of Biomedical Research. 27: 167- 175, 1993.
  4. Levine, B. et al. Experimental and Clinical Performance of Porous Metal Tantalum in Orthopedic Surgery. Biomaterials. 27: 4671-81, 2006.
  5. Zimmer ZRR_WA_2537_12.
  6. Internal Persona Knee Cumulative Sales Report – Sales Globally as of May 2019.
  7. Statement based on: 5 million implantations7h 300+ Publications7g 100% Survivorship at 17 Years Lowest revision rate7b-e Benchmark for PROMs7f 10A* ODEP rating for CR and PS knees both with and without patella7g Every 90 seconds a patient receives a NexGen knee7h 1 in 5 knees implanted globally is a NexGen Knee7i  7a. Kim, Y.H., et al. Cementless and cemented total knee arthroplasty in patients younger than fifty five years. Which is better? International Orthopaedics (SICOT) (2014) 38:297–303. 7b. Australian Orthopaedic Association National Joint Replacement Registry. Annual Report. Adelaide.AOA 2016: Table KT9 Cumulative Percent Revision of Primary Total Knee Replacement with Cement Fixation. 7c. Australian Orthopaedic Association National Joint Replacement Registry. Annual Report. Adelaide.AOA 2016: Table KT10 Cumulative Percent Revision of Primary Total Knee Replacement with Cementless Fixation. 7d. Australian Orthopaedic Association National Joint Replacement Registry. Annual Report. Adelaide. AOA 2016: Table KT11 Cumulative Percent Revision of Primary Total Knee Replacement with Hybrid Fixation. 7e. Select variants from the 2016 Swedish National Registry available at http://myknee.se/en/ (pgs 42-43). 7f. Baker, P.N., et al. The effect of surgical factors on early patient-reported outcome measures (PROMs) following total knee replacement. J Bone Joint Surg Br. 94:1058, 2012. 7g. Latest ODEP ratings can be found at http://www.odep. org.uk. 7h. 2015 Sales data available at Zimmer Biomet. 7i. EMBASE search: «NexGen» AND «Knee».
  8. Seidenstein A, Birmingham M, Foran J, Ogden S. Better accuracy and reproducibility of a new robotically-assisted system for total knee arthroplasty compared to conventional instrumentation: a cadaveric study. Knee Surg Sports Traumatol Arthrosc. 2020 May 24. doi: 1007/s00167-020- 06038-w. Epub ahead of print. PMID: 32448945. Cadaveric testing is not necessarily indicative of clinical performance
  9. Parratte, S., et al. Instability After Total Knee Arthroplasty. Journal of Bone Joint Surgery (America). 90(1): 184, 2008. Cadaveric testing is not necessarily indicative of clinical performance.