Biologic Treatment for Early Intervention and Cartilage Repair.

DeNovo NT Graft is a particulated juvenile cartilage implant used for the repair of articular cartilage damage. It is intended to provide surgeons with an early-intervention option for articular cartilage repair.


  • Cartilage Repair


  • Biologics


  • Knee
  • Hip
  • Ankle
  • Shoulder

DeNovo NT Graft is an FDA-listed tissue product used for knee, hip, ankle and shoulder cartilage restoration since 2007 with no reports of graft rejection or disease transmission.

Survivorship at 5 years


in knees.1

Survivorship at 5 years


in ankle.2


For any inquiries regarding reimbursement, please contact Zimmer Biomet Reimbursement Hotline: Phone: 1-866-946-0444. Hotline Hours: Monday-Friday, 8am- 5pm, EST




Single-stage Procedure 1

  • Allows for a single-stage procedure with fibrin fixation, eliminating the need for harvesting periosteal flap, tissue or cells from areas of undamaged cartilage

Juvenile Allograft Cartilage Advantage

  • Juvenile allograft cartilage contains 10x greater chondrocyte density than adult tissue and does not elicit an allogeneic immune response3-5*

Additional Information

Tailored resources for your patients.

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For product information, including indications, contraindications, warnings, precautions, potential adverse effects and patient counseling information, see the package insert and information on this website. To obtain a copy of the current Instructions for Use (IFU) for full prescribing and risk information, please call 1-800-348-2759, press 4 for 411 Technical Support.