This site uses cookies to make your web experience a great one.Learn More

The cookie settings on this website are currently set to allow certain types of cookies. We do not use cookies for targeted or behavioral advertising on this website. Those cookies that we do use are designed to permit you to use the site functions and browse our site in the way that is favorable to you. If you continue without changing your cookie settings, you consent to that. However, you can change your cookie setting at any time.

Clotalyst® Autologous Activation Solution


The Clotalyst Autologous Activation System rapidly produces up to 10 ml of autologous clotting factors from 12 ml of the patient’s blood at the point-of-care. When combined with the leukocyte-rich platelet–rich plasma (L-PRP) produced by the GPS III Platelet Concentration System, the autologous clotting factors from the Clotalyst Autologous Activation System activate platelets and initiate fibrin formation and cross-linking to form a platelet gel in under 15 seconds.

Zimmer Biomet Biologics has re-designed the Clotalyst® Autologous Serum System to the new and improved Clotalyst® Autologous Activation System. The key features of the new design include:

Autologous Activation Solution

  • No pooled or bovine sources
  • Eliminates risk of bovine spongiform encephalopathy (BSE)
  • Eliminates potential source related coagulopathies


  • Minimal steps required for processing
  • No heating step required
  • No centrifugation step required


  • Consistently produces up to 10 ml of activation solution
  • Clots platelet-rich plasma in less than 15 seconds
  • Activation solution stable up to four hours after preparation

Convenient Design

  • Single use disposable device
  • No additional mechanical processing required
  • Total processing time of less than 20 minutes

Additional Information

Legal Manufacturer:                      

Biomet Orthopedics
56 East Bell Drive
P.O. Box 587
Warsaw, Indiana 46581 USA

All content herein is protected by copyright, trademarks and other intellectual property rights, as applicable, owned by or licensed to Zimmer Biomet or its affiliates unless otherwise indicated, and must not be redistributed, duplicated or disclosed, in whole or in part, without the express written consent of Zimmer Biomet.  
This material is intended for health care professionals. Distribution to any other recipient is prohibited.
For product information, including indications, contraindications, warnings, precautions, potential adverse effects and patient counseling information, see the package insert and information on this website. To obtain a copy of the current Instructions for Use (IFU) for full prescribing and risk information, please call 1-800-348-2759, press 4 for 411 Technical Support.