When You Need to Know Now

The first of its kind, the Synovasure Alpha Defensin Lateral Flow Test is specifically designed as an aid for the diagnosis of periprosthetic joint infection (PJI). The test delivers same day results with speed and accuracy.


  • Infection Diagnostics


  • Revision Knee 
  • Revision Hip

The Synovasure Alpha Defensin Lateral Flow Test offers a rapid and accurate positive/negative result (10 minutes) to aid in diagnosis of PJI.



vs. sensitivity standard of care criteria1



vs. specificity standard of care criteria1*

* Excluding samples with >20% blood

Product Features

The Synovasure Alpha Defensin Lateral Flow Test is a standalone, rapid device for detecting alpha defensin in synovial fluid. The test received FDA authorization in 2019 as a CLIA moderately complex test.


Same-Day Results

Results in 10 minutes following performance of test


Performance Backed by Data

Demonstrates a high sensitivity (94.3%) and specificity (94.5%). In addition, results proven in clinical studies to be unaffected by:

  • Prior antibiotic administration1,3,4
  • Comorbidities related to inflammation1,3,5
  • Type and/or virulence of the organism1,3,6


Minimal Fluid Requirement

Only needs 15 microliters of synovial fluid to perform test


Consistent results to Laboratory Test

No statistically significant difference in performance of Synovasure Alpha Defensin Lateral Flow Test and Synovasure Alpha Defensin ELISA laboratory test.1


Synvosure Alpha Defensin Lateral Flow Test

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Additional Information

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