Gel-One® Cross-linked Hyaluronate is a 100% cross-linked gel, allowing for better cushioning and greater product durability1 in a single 3mL injection, giving healthcare providers confidence in addressing mild to moderate OA of the knee with a safe, effective and complete treatment.
Procedures
Philosophies
Application
Effective Pain Relief: 100% cross-linked, high molecular weight gel, offering increased product durability, cushioning and resistance to diffusion1
Easy-to-Use: Single injection with only 3mL treatment volume
Proven Safety Profile: Safe for repeat use with no increased risk of side effects2,3,5,6
Gel-One is a sterile, transparent and viscoelastic hydrogel. It is a cross-linked hyaluronate (also referred to as hyaluronan, hyaluronic acid, or HA).
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Indications For Use
Gel-One Hyaluronate is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, non-steroidal anti-inflammatory drugs (NSAIDs) or simple analgesics, e.g., acetaminophen.
Important Safety Information
Before using Gel-One Hyaluronate, ask your patients if they are allergic to hyaluronan products, cinnamon, or products from birds such as feathers, eggs, and poultry. Gel-One Hyaluronate is only for injection into the knee, performed by a doctor or other qualified health care professional. Gel-One Hyaluronate injection should not be used in the presence of a skin disease or infection around the area where the injection will be given. Gel-One Hyaluronate has not been tested to show pain relief in joints other than the knee and for conditions other than OA. Gel-One Hyaluronate has not been tested in patients who are pregnant, mothers who are nursing, or anyone under the age of 21. Strenuous or prolonged weight-bearing activities after treatment are not recommended. The effectiveness of repeat treatment cycles of Gel-One Hyaluronate has not been established. The side effects most commonly seen after injection of Gel-One Hyaluronate in the clinical trial were knee pain, swelling, and/or knee effusion.
These reactions are generally mild and do not last long. For complete instructions for use, see the package insert.
This material is intended for US Health Care Professionals.
Gel-One is a registered trademark of Seikagaku Corporation.
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This material is intended for health care professionals. Distribution to any other recipient is prohibited.
For product information, including indications, contraindications, warnings, precautions, potential adverse effects and patient counseling information, see the package insert or contact your local representative; search this website for additional product information. To obtain a copy of the current Instructions for Use (IFU) for full prescribing and risk information, please visit labeling.zimmerbiomet.com or call 1-800-348-2759, press 4 for 411 Technical Support.
